IM8 Daily Ultimate Essentials Pro

A Daily Foundation for Cellular Energy and Gut Function

You wake up tired. You eat clean. Your labs come back “normal.” And still, something is off.

That gap between how you feel and what your labs say is where mitochondrial dysfunction and gut dysbiosis usually live. Both run on the right vitamins, minerals, and compounds (cofactors) delivered every day in usable forms and at meaningful doses. IM8 Daily Ultimate Essentials Pro is a 12g powder built around those inputs: over 90 active ingredients, clinically dosed cofactors, a 10 billion CFU probiotic blend, and a cellular defense complex. The formula is produced by Prenetics (NASDAQ: PRE), a publicly listed health sciences company, and tested in a 12-week randomized trial (NCT06655597).

This is a nutritional foundation, not a Long COVID treatment. It will not replace the mechanism work you do with your doctor. What it can do is make sure your cells have the raw materials they need while that work happens.

How It Works

Mitochondrial energy depends on cofactors your daily food often cannot deliver at therapeutic doses. Your mitochondria produce ATP, the energy currency your body runs on. To produce it, they need specific vitamins and minerals in forms your body can actually use. Essentials Pro provides CoQ10 at 100 mg, magnesium bisglycinate at 100 mg, methylcobalamin B12 at 200 mcg, methylfolate at 400 mcg DFE, and the bioactive forms of B2 (R5P) and B6 (P5P). MSM at 1,500 mg, L-glycine at 3g, and taurine at 2g support the same cellular pathways.

Gut barrier function depends on the right bacterial strains reaching the colon alive. Most probiotics die in stomach acid before they get there. Essentials Pro uses 10 billion CFU of Bacillus coagulans BC99 and Bacillus subtilis DE111, both spore-forming strains surviving stomach acid intact. Lactobacillus casei at 25 mg and a digestive enzyme blend round out the gut support. Inulin acts as a prebiotic feeding the strains once they reach the colon.

Cellular defense depends on a steady supply of antioxidants and stress regulators. Long COVID drives oxidative load and stuck stress signaling. Vitamin C at 900 mg, zinc, selenium, elderberry, reishi, and grape seed handle the immune-facing side. The CRT8 complex (berberine, astaxanthin, pomegranate, spermidine, resveratrol, turmeric) targets cellular aging signals and oxidative load. The adaptogens (American ginseng, andrographis, rhodiola) modulate the stress response driving symptom flares in post-viral illness.

Why Dr. Groysman Recommends IM8 Essentials Pro

Dr. Groysman treats Long COVID patients at COVID Institute. Mitochondrial dysfunction and gut dysbiosis are two of the six mechanisms he works through with every patient.

“Patients come in exhausted, with brain fog, with digestion that has fallen apart since their infection. Two of the six mechanisms I always check are mitochondrial function and gut barrier integrity. Both need cofactors and inputs your daily diet often cannot provide at meaningful doses. I want my patients on CoQ10. I want them on bioactive Bs. I want them on a probiotic strain with strain-level identification, not a generic blend. IM8 Essentials Pro covers those in one daily powder. In IM8’s 12-week clinical trial (NCT06655597, n=60), 95% of participants reported a noticeable daily boost, 85% experienced better digestion, and 80% reported improved sleep quality. Those are participant-reported outcomes, not biomarker shifts. I read them as supportive, not definitive. The formula covers what I want covered, at doses I would otherwise have to source separately. That is why it is here.”

The price point lands where it does because consolidation costs less than buying these cofactors separately. Sourcing therapeutic-dose CoQ10, bioactive methylated B vitamins, magnesium bisglycinate, a clinical-grade strain-identified probiotic, and a CRT8-equivalent antioxidant complex through individual bottles usually runs $120 to $160 per month. IM8 consolidates them at $89 on the 30-day subscription or $78 on the 90-day, with NSF Certified for Sport screening on top.

The NSF Certified for Sport designation matters in its own right. It means the formula is screened for 280+ banned substances, heavy metals, and label accuracy by an independent lab. For patients sensitive to contaminants or who get drug-tested, that screen is one of the stricter standards available.

Who May Benefit

You may benefit from IM8 Essentials Pro if:

• You are working through Long COVID with your doctor and want a foundational supplement covering the mitochondrial and gut cofactors
• You are dealing with post-viral fatigue or brain fog and your daily diet does not cover CoQ10, bioactive Bs, magnesium, and a clinically dosed probiotic
• You have gut symptoms (bloating, irregular stools, food sensitivities) and want a probiotic with strain-level identification plus a prebiotic
• You are sensitive to supplement contaminants and want NSF Certified for Sport screening
• You are tired of managing 8 separate bottles and want one daily powder consolidating the foundation
• You are navigating chronic stress, poor sleep, or low energy and standard multivitamins have not been enough

Important Context

IM8 Daily Ultimate Essentials Pro is a dietary supplement. It is not a medical device, not a prescription, and is not intended to diagnose, treat, cure, or prevent any disease or condition. These statements have not been evaluated by the Food and Drug Administration.

Do not start IM8 Essentials Pro without checking in with your doctor first if any of the following apply to you:

• You are pregnant or nursing. Clear it with your OB or midwife before adding any new supplement on top of your prenatal.
• You are on blood thinners like warfarin. Reishi mushroom and grape seed extract can interact and shift your INR.
• You are on antihypertensive medication. Some of the adaptogens (rhodiola, ginseng, andrographis) and other ingredients can affect blood pressure.
• You have an active autoimmune flare. Andrographis can modulate immune signaling. Wait until you are stable and discuss timing with your specialist.
• You are already on prescribed supplements. Check for overlap on fat-soluble vitamins (A, D, E, K) so you do not double-dose.
• You are under 18. The formula is built for adults, not children.
• You are in the middle of an acute illness. Wait until you are stable before starting a new daily supplement.

If you feel worse after starting it, stop and contact your doctor. If you are working with a physician on Long COVID or another chronic condition, share the full ingredient list with them before you begin. HSA and FSA eligibility is reported by IM8 with a 98% approval rate, listed here as a factual product detail and not as financial or insurance advice.